Seasoned adventurer Dirk Pitt (Matthew McConaughey) sets out for the African desert with his sarcastic companion (Steve Zahn) in search of a ship rumored to have vanished long ago, the main draw being the treasure supposedly hidden within the lost vessel. When the daring duo come across a beautiful scientist (Penélope Cruz) who is juggling an escape from a warlord and a mission to stop the spread of a powerful plague, their desert expedition begins to heat up.
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